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Mutations in the IL-12Rβ1 gene accounts for 38% of cases of MSMD
The enzyme is expressed by various cell types
VPQKPKVSLNPPWNRIFKGENVTLTCNGNNFFEVSSTKWFHNGSLSEETNSSLNIVNAKFEDSGEYKCQHQQVNESEPVYLEVFSDWLLLQASAEVVMEGQPLFLRCHGWRNWDVYKVIYYKDGEALKYWYENHNISITNATVEDSGTYYCTGKVWQLDYESEPLNITVIKAPREKYWLGGGSGGGSPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
k Isotype Control Invivo rat IgG2a isotype control Application ELISA
The role of CD6 in autoimmune diseases may specifically reflect its interaction with CD318
Fas/TNFRSF6/CD95 Fc Chimera Protein, Rat Size:100μg Mutations in the IL-12Rβ1 geneProduct Specification Species Rat Synonyms FAS,ALPS1A,APO1,APT1,CD95,FAS1,FASTM,TNFRSF6,FasR Accession NP_631933. 2 Amino Acid Sequence Gln22 Lys170, with hIgG Fc Expression System HEK293 Molecular Weight 50 70kDa(R) Purity 95% by SDS PAGE & SEC HPLC Conjugation Unconjugated Tag Human Fc Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, PH7. 4, 5% trehalose Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure
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